• June 2022

PhD position: Do you want to get trained in a field with a bright future, and ultimately contribute to a more sustainable world? Then join us for a PhD in biophysical studies of plant seed storage proteins, in the framework of the SEEDFOOD project.

  • May 2022

Our pre-print on “Mass photometric detection and quantification of nanoscale α-synuclein phase separation” is now online on the BiorXiv. Soumik has been able to directly visualize nanometric clusters (see picture above) that act as pre-cursors for macroscopic droplets of alpha-synuclein LLPS.

Our whole SEEDFOOD crew (Alex, Kyu, Wang, Lars) attends the SEEDFOOD kick off meeting at the University of Copenhagen. Two nice days of science and fund. Great to meet everybody who is on board SEEDFOOD.

Alex, Rasmus and Soumik attend the conference “Cellular mechanisms driven by phase separation” in Heidelberg at the EMBL. Great opportunity to discuss our latest work with the expert community.

Celina Schulz finishes her short visit and goes back to Düsseldorf University.

Abigail Barclay finishes her short visit and goes back to the University of Copenhagen.

  • April 2022

Celina Schulz joins our group as visiting PhD student from the Heinrich Heine University Düsseldorf. Celina works in the group of Prof. Wolfgang Hoyer and explores mechanisms of inhibition of alpha-synuclein amyloid fibril formation by affibodies.

Abigail Barclay joins group as a visiting PhD student from the group of Prof. Lise Arleth at the Niels Bohr Institute of the University of Copenhagen.

Alex, Kyu and Wang attend the Food Colloid conference in Lund. Fast track into the field of food science that we have entered through the SEEDFOOD project.

  • March 2022

Christin Pohl joins the group as a DFF funded postdoc. She will be working at Lund University in the group of our collaborator Sara Linse.

Start of our project on improved seed amplification assays for disease diagnostics, funded by the MJFF foundation, and in collaboration with the company Lundbeck.

Soumik is awarded a prestigious Marie Curie postdoc grant. Amazing, and well done Soumik. We are very much looking forward to having you around for another two years!

  • February 2022

Alex’s review paper on amyloid thermodynamics is now online in Chemical Science, as editor’s pick of the week!

Shuangyan Wang joins the group as postdoc in the SEEDFOOD project, from ETH Zurich. Welcome Wang!

Lars joins group as Master’s student in the SEEDFOOD project. Lars has already done a special course with us. Welcome back!

  • January 2022

New member-Our first employee of the SEEDFOOD project, Suk Kyu Ko, joins our group. Welcome Kyu!

Our first publication of 2022 is online at ACS Nano. Nice collaboration with Hossein Mohammad-Beigi. Hossein was able to perform a detailed characterization of a protein corona on the ability of polymer nanoparticles to facilitate the nucleation of alpha-synuclein amyloid fibrils.

  • December 2021

Alexander gives seminars at the Centre for Misfolding Diseases (Cambridge, UK) annual meeting, at DTU Biosustain and at the company Novozymes

Our postdoc, Soumik writes a behind the paper commentary on the Capflex paper in Springer Nature protocols and methods community.

Our publication presenting our new method to study protein liquid-liquid-phase separation, Capflex, is published in Nature Communications. Congratulations to Emil, Soumik, Rasmus, Jacob and Azad. Great teamwork, and the fist publication with research 100% performed at DTU.

Our guest PhD student from Amsterdam, Juami van Gils, leaves again. It was great to have had you around, Juami. All the best!

Our PhD student Jacob receives funding for an extended stay at the Technion in Haifa, in the laboratory of Prof. Meytal Landau. Congratulations, Jacob!

  • November 2021

Most of our group attends the Linderstrøm-Lang Centre Symposium at the University of Copenhagen. It is nice to attend an in person meeting and network with the Danish biophysics community!

Our PhD student Rasmus goes on a scientific visit to the group of Prof. Simon Alberti at the University of Dresden. Have fun in one of the leading centers of protein condensate research!

  • October 2021

Our PhD students Rasmus and Jacob give a joint presentation at the FIDAbio user meeting in Copenhagen. They talk about our new method, Capflex, which allows detailed and high throughput studies of protein liquid-liquid phase separation.

New member-Juami van Gils, a PhD student from Amsterdam joins the group as a guest PhD student for three months. Welcome Juami!

Alexander is awarded an Ascending Investigator grant from the Lundbeck Foundation. This will enable us to work for the next 4 years on the role of amyloid fibril thermodynamic stability in neurodegeneration. Big thank you to the Lundbeck Foundation.

  • September 2021

Postdoc position for an experimentalist who has experience in recombinant protein production and wants to learn some advanced biophysics. We offer a 2+1 year postdoc position at DTU Bioengineering and the work will be carried out in collaboration DTU Biosustain. You would produce and study rapeseed proteins for a deep understanding of their properties and interactions, with the final aim to enable their use in food

Are you a computational biophysicist and you want to make a difference in the transition towards a more sustainable food production? Then get in touch! We have a one year postdoc position to help us get started with our ambitious SEEDFOOD project, funded by the NNF. You would be doing simulations and structural analysis to help us guide our experiments.

We are soon going to start working on the Biophysics of plant seed storage proteins, in the context of the project SEEDFOOD, led by Marianne Nissen Lund of the University of Copenhagen’s department of Food Science. Our contribution to SEEDFOOD will be a biophysical characterization of these types of proteins and their interactions with other components relevant for food, such as lipids or saliva components, at unprecedented levels of detail.

New member-Lars Boyens-Thiele joins the group as a project student. Welcome Lars!

  • August 2021

New member-Tom Mason joins the lab as a postdoc and he will help us with our various microfluidics-related projects. Welcome Tom!

  • July 2021

Our paper on a de novo sequencing workflow of immunoglobulin light chains by mass spectrometry is accepted in Analytical Chemistry! Great collaboration with Julia Chamot-Rooke’s team at the Institut Pasteur in Paris.

  • June 2021

New member-Azad Farzadfard joins the lab and he will work on alpha-synuclein amyloid fibril formation. Welcome Azad!

The SEEDFOOD project, in which we are co-applicant, is granted by the NNF! 6 years ahead of us in which we can explore the basic biophysics of plant seed storage proteins with the aim to transform them ultimately into something fit for human consumption.

  • April 2021

New member-Soumik Ray joins the lab as a postdoc and he will work on massive exploration of the sequence space of protein liquid-liquid phase separation. Welcome Soumik!

  • March 2021

Alex gives an online presentation at the LINXS Amyloid workshop – Heart and Mind: linking in vitro science to the clinical context.

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